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Both,,extended,,insights,,into,,the,,biology,,of,,this,,disease,,association,,and,,improved,,strategies,,to,,treat,,hematologic,,disorders,,in,,primary,,mediastinal,,nonseminomatous,,germ,,cell,,tumors,,should,,be,,areas,,of,,further,,investigation.,,The,clonal,relationship,between,a,mediastinal,germ,cell,tumor,and,acute,myelogenous,leukemia,was,supported,by,another,case,reported,by,Woodruff,et,al.,^,,a,,b,,Cabot,,,Richard,,C,,(1919).,,54-61.,,(23),,Ashby,,MA,,,Williams,,CJ,,,Buchanan,,RB,,,Bleehen,,NM,,,Arno,,J.,,198,,(6):,,85162.,,Therapy,in,stage,I,tumors,consists,of,surgical,resection,with,good,prognosis.,

Serum,,,concentrations,,,of,,,the,,,tumor,,,markers,,,AFP,,,,-HCG,,,,and,,,LDH,,,were,,,elevated,,,in,,,82%,,,,41%,,,,and,,,47%,,,of,,,the,,,17,,,patients,,,,respectively.,,,Hartmann,,,Craig,,R.,,In,patients,with,myelodysplasia,with,abnormal,megakaryocytes,,patients,presented,either,with,pancytopenia,or,with,isolated,thrombocytopenia.,View,this,table:,In,this,window,In,a,new,window,Table,2.,Fizazi,,,Institut,,Gustave-Roussy,,,Villejuif,,,France;,,L.,,To,,,determine,,,the,,,number,,,of,,,new,,,cases,,,of,,,leukemia,,,expected,,,in,,,the,,,study,,,group,,,,we,,,used,,,5-year,,,age,,,group-specific,,,data,,,from,,,the,,,cancer,,,registry,,,of,,,the,,,Federal,,,state,,,of,,,Saarland,,,,located,,,in,,,southwest,,,Germany,,,,from,,,1975,,,through,,,1996.,,,MedlineWeb,,of,,Science,,(41),,Brox,,AG,,,Lavallee,,MC,,,Arseneau,,J,,,Langleben,,A,,,Major,,PP.,,Accepted,,November,,3,,,1999.,,Hematologic,malignancies,associated,with,primary,mediastinal,germ-cell,tumors.,Nichols,,Oregon,Health,Sciences,University,,Portland;,J.-P.,

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